![]() In 2016, sertraline was the most commonly prescribed psychiatric medication in the United States and in 2018, it was the fourteenth most commonly prescribed medication in the United States, with over 38 million prescriptions. Sertraline was invented and developed by scientists at Pfizer and approved for medical use in the United States in 1991. ![]() The efficacy of sertraline for depression is similar to that of other antidepressants, and the differences are mostly confined to side effects. Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
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